Acta Veterinaria 24. (1974)
3. szám - ATTALAH, O. A. - MOSSALAM, I. - ABDEL-RAHMAN, M. S.: Visceral larva migrans of Neoascaris vitulorum in laboratory animals
Acta Veterinaria Academiae Scientiarum Hungaricae, Tomus 24 (3), pp. 207—220 (1974) VISCERAL LARVA MIGRANS OF NEOASCARIS VITULORUM IN LABORATORY ANIMALS By O. A. Atallah, I. Mossalam and M. S. Abdel-Rahman Pathology, Microbiology and Parasitology Dept. Faculty of Vet. Med. El Zagazig and Pathology and Parasitology Department Faculty of Vet. Med. Cairo University (Received March 19, 1973) The reactions to parasites of man in abnormal hosts have been extensively studied. The reverse situation, in which man himself is the abnormal host for parasites of other animals, has received considerably less attention. A few cases were reported by Takata (1951), and Mendheim et al. (1952) in which animal ascarids have infected humans and developed to sexual maturity in much the same manner as in their normal hosts. Due to its rarity, the importance of this type of infection is relatively small, yet, it cannot be overlooked. On the ground of a study of cutaneous larva migrans Beaver et al. (1952) believe that various nematode larvae behave similarly both in man and animals. More important phenomena of animal ascarid infection in humans involve the type called visceral larva migrans by Beaver et al. (1952). Beaver (1954), Smith and Beaver (1953) and Beaver (1956) suggest that this condition may exist more frequently than is commonly presumed, especially in children. Dent et al. (1956) state that the close association of young children with dogs and cats establishes an ideal set of circumstances under which infective ova may be ingested. The infective eggs of Neoascaris vitulorum may cause the same syndrome when swallowed by the farmers living in close contact with the farm animals, especially cattles and buffaloes. The present authors have undertaken a fundamental study on the progress of histopathological changes in the laboratory animals experimentally infected with N. vitulorum. Materials and Methods Rabbits, guinea pigs, rats and chickens of 40, 75, 20 and 7-day-oldrespectively, were used in this work. Five individuals from each species were experimentally infected with about 5000 infective eggs of Neoascaris vilulorum. One animal of each group was slaughtered 1, 2, 3, 7 and 10 weeks after infection. The methods of obtaining eggs, infection and processing tissues are the same as described by Mossalam et al. (1971 and 1972). Acta Veterinaria Academiae Scientiarum Hungaricae 24, 1974