Acta Veterinaria 33. (1985)

1-2. szám - VIROLOGY - BOROS, G. - GRAF, Z. - BENKŐ, MÁRIA - BARTHA, A.: Isolation of a bovine adenovirus from fallow deer (Dama dama)

Acta Veterinaria Hungarica 33 (1—2), pp. 119 — 123 (1985) ISOLATION OF A BOVINE ADENOVIRUS FROM FALLOW DEER (DAMA DAMA) G. Boros1, Z. Graf2, Mária Benkő3 and A. Bartha3* ‘Department of Pathology, University of Veterinary Science, H-1400 Budapest, P. O. Box 2; 2Veterinary Office of the Budapest Veterinary Station at the Budapest Zoo, H-1146 Budapest, Állatkerti út 6/12; and 3Veterinary Medical Research Institute of the Hungarian Academy of Sciences, H-1581 Budapest, P. O. Box 18, Hungary (Received October 22, 1984) A type 6 bovine adenovirus of subgroup II was isolated in calf testicle cell culture from the lungs and trachea of a succumbed fallow deer (Dama dama), which had been kept in the Budapest Zoo, in a group of fallow deers showing mild respiratory symptoms. Convalescent sera of the surviving animals contained no antibodies to infectious bovine rhinotracheitis (IBR), respiratory syncytial (RS) and parainfluenza-3 (PI-3) viruses; however, antibodies to type 2 and 6 bovine adenoviruses were detectable. Based upon the characteristic gross pathological and histopathological changes, the demonstration of virus-neutralizing antibodies in the convalescent sera and the isolation of adenovirus it can be postulated that the primary cause of the respiratory disease was the type 6 bovine adenovirus. Keywords. Bovine adenovirus, isolation, fallow deer (Dama dama), respiratory disease. Soon after the isolation and characterization of bovine adenoviruses from healthy cattle (Klein et al., 1959), these viruses were brought into causal rela­tionship with the so-called pneumoenteritis of calves, a disease manifesting itself in respiratory and digestive symptoms (Bartha and Áldásy, 1964; Áldásy et al., 1964; Darbyshire et al., 1965). After several authors had reported the worldwide prevalence of adenovirus infeetion of cattle, Bélák and Pálfi (1974) established the causative role of type 2 bovine adenovirus in the pneumoenteri­tis of sheep. More recently, Baber and Condy (1981) isolated type 3, 4 and 8 bovine adenoviruses from the nasal secretions of free-living, healthy Caffre buffaloes (Syncerus cnffer). The infection of other animal species has been demonstrated by results of serological surveys; e.g. Elazhary et al. (1981) demonstrated virus-neutralizing antibodies to bovine adenovirus in a caribou (Rangifer tarandus caribou) herd in Canada. In the present paper isolation of a type 6 bovine adenovirus from the; organs of a fallow deer died of respiratory disease is reported. * to whom reprint requests should be addressed

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